Prevalence and incidence of depressive, anxiety, and insomnia symptoms in perimenopausal and postmenopausal women: Systematic review and meta-analysis.

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◆ 논문 초록 (Abstract)

BACKGROUND: Menopausal transition represents a vulnerable stage for women’s mental health. Yet, global epidemiological estimates of psychological morbidity across perimenopausal and postmenopausal periods remain limited. OBJECTIVE: To systematically synthesise the pooled prevalence and incidence of depressive, anxiety, and insomnia symptoms in perimenopausal and postmenopausal women. METHODS: We systematically searched MEDLINE, EMBASE, and SCOPUS until December 2024 for cross-sectional and cohort studies reporting point or period prevalence or incidence of depressive, anxiety, or insomnia symptoms. Random-effects models generated pooled estimates with 95% confidence intervals (CI). Subgroup analyses were performed by assessment type and duration of menopause. Risk of bias was evaluated using the Newcastle-Ottawa Scale. RESULTS: A total of 102 studies (N = 1,141,955) were meta-analysed. The pooled point prevalence of depressive symptoms was 32% (95% CI, 26%-37%) in perimenopausal and 30% (95% CI, 27%-34%) in postmenopausal women; the period prevalence was 24% (95% CI, 20%-29%) and 19% (95% CI, 15%-23%), respectively. The corresponding incidence rates were 13% (95% CI, 7%-22%) and 5% (95% CI, 2%-10%), respectively. Anxiety point prevalence was 29% (95% CI, 15%-45%) in perimenopausal and 39% (95% CI, 22%-57%) in postmenopausal women. Point prevalence of insomnia was 42% (95% CI, 34%-50%) and 27% (95% CI, 19%-37%) among postmenopausal and perimenopausal women, respectively. Subgroup analyses revealed higher rates with screening instruments and during early menopause. Most studies had a low or moderate risk of bias. CONCLUSIONS: Nearly one in three women experiences depressive, anxiety, and/or insomnia symptoms around menopausal transition, underscoring the need for routine mental health screening and integrated multidisciplinary care.

◆ 원문 정보
저널: Gen Hosp Psychiatry
연도: 2026

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