The Impact of Sleep Quality on Skin Color
이 페이지는 아래 학술 논문의 초록(Abstract) 전문을 제공합니다. 원문은 하단 링크에서 확인하세요. ◆ 논문 초록 (Abstract) Sleep plays a crucial role in regulating immune, endocrine, and skin functions. Increasing evidence suggests that sleep...
이 페이지는 아래 학술 논문의 초록(Abstract) 전문을 제공합니다. 원문은 하단 링크에서 확인하세요.
◆ 논문 초록 (Abstract)
Sleep plays a crucial role in regulating immune, endocrine, and skin functions. Increasing evidence suggests that sleep deprivation and circadian rhythm disruption can impact skin pigmentation by influencing melanocyte biology, hormonal balance, and inflammatory pathways. Clinical observations and molecular studies have revealed links between poor sleep and various pigmentary disorders. However, the underlying mechanisms remain incompletely understood, and the causal relationships are still under debate due to physiological confounders such as psychological stress and metabolic dysregulation. This review summarizes recent findings from experimental, clinical, and epidemiological studies on the relationship between sleep quality and skin pigmentation. Relevant literature was retrieved through PubMed and cross-referenced sources, focusing on research involving melanocyte activity, circadian genes (e.g., PER1 , BMAL1 ), hypothalamo-pituitary axis (HPA) activation, and pigmentation-related dermatological conditions. Both human and animal studies were included. Poor sleep has been shown to alter skin parameters including melanin, hemoglobin, hydration, and trans-epidermal water loss, often through keratinocyte barrier impairment and microbiome imbalance. Disruption of the HPA leads to elevated cortisol and proinflammatory cytokines, further affecting melanogenesis. Clinically, sleep disturbances are associated with pigmentary disorders such as melasma, rosacea, floppy eyelid syndrome, and acanthosis nigricans. Obstructive sleep apnea contributes to pigmentation changes via hypoxia-induced inflammation and vascular remodeling. A newly described disorder, maturational dyschromia, may also involve habitual sleep patterns. Future research integrating wearable technology and artificial intelligence-based skin imaging may enable real-time, individualized assessment of sleep-pigmentation interactions.
◆ 원문 정보
저자: Xu J, Cai X, Qiao J, Fang H
저널: Indian Dermatol Online J
연도: 2025
DOI: 10.4103/idoj.idoj_1011_24
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