A feasibility study of the effects of concurrent transcranial direct current stimulation (tDCS) on mindfulness training in adults living with overweight or obesity: the MINDED trial protocol
이 페이지는 아래 학술 논문의 초록(Abstract) 전문을 제공합니다. 원문은 하단 링크에서 확인하세요. ◆ 논문 초록 (Abstract) BACKGROUND: This study protocol describes the use of two brain-directed treatments, i.e. mindfulness training (MT) and...
이 페이지는 아래 학술 논문의 초록(Abstract) 전문을 제공합니다. 원문은 하단 링크에서 확인하세요.
◆ 논문 초록 (Abstract)
BACKGROUND: This study protocol describes the use of two brain-directed treatments, i.e. mindfulness training (MT) and transcranial direct current stimulation (tDCS), as interventions for obesity-related behaviours (e.g. food craving, over-eating). Individually, mindfulness and tDCS are promising interventions for addressing maladaptive eating behaviours. We hypothesise that clinical outcomes from MT and tDCS will be improved when the two interventions are combined. METHODS: This protocol is described in accordance with SPIRIT guidelines for clinical trials. The study is a feasibility double-blind randomised sham-controlled (RCT) trial of MT concurrent with or without self-administered tDCS in adults with obesity/overweight (BMI ≥ 25 kg/m2) (the MINDED trial). Sixty-six adults will be randomly allocated to one of three groups: MT with active tDCS, MT with sham tDCS or waiting list control. Participants in both intervention arms will be asked to complete daily app-based MT for 8 weeks post-randomisation. They will also receive 10 sessions of active or sham tDCS over the first 3 weeks post-randomisation. On tDCS-days, MT will be delivered concurrently. Feasibility will be evaluated by recruitment, retention, and follow-up rates. Acceptability will be determined by monitoring side effects and by participant ratings. Clinical and cognitive outcomes (e.g. body fat percentage and working memory) will be assessed at baseline (T0), 3 weeks post-randomisation (T1) and 8 weeks post-randomisation (T2). DISCUSSION: The study will establish the feasibility of conducting a large-scale RCT of (MT + real tDCS) in adults with BMI ≥ 25 kg/m2 classified as overweight or obese. This will involve assessing recruitment, retention and follow-up rates together with measures of acceptability and credibility. It will provide preliminary evidence on the clinical efficacy of the concurrent administration of tDCS and MT for people with obesity/overweight and preliminary information on possible underlying mechanisms (e.g. change in neurocognitive outcomes). TRIAL REGISTRATION: ClinicalTrials.gov Identifier (NCT number): NCT05865912. Registered on 19 May 2023.
◆ 원문 정보
저자: Ageeli M, Flynn M, Lopes M, İnce B, Alves D et al.
저널: Pilot Feasibility Stud
연도: 2026
DOI: 10.1186/s40814-025-01748-9
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