Moisturizers

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◆ 논문 초록 (Abstract)

Moisturizers can be defined as topical formulations containing substances that are intended to increase the hydration of the skin and restore its natural protective barrier function. Moisturizers are commonly used in dermatology to treat and prevent various skin conditions, such as eczema, xerosis, lichen simplex, etc. The stratum corneum, the outermost layer of the epidermis, is the primary physiologic barrier of the skin and is of critical importance in maintaining water balance. The role of water within the stratum corneum is pivotal to maintaining normal skin integrity and turnover. Water allows for the increased flexibility of the tissues and is a crucial component of the enzymatic reactions responsible for the cleavage of corneodesmosomal connections between corneocytes during the desquamation process. Below a critical water concentration, the corneodesmosomal connections remain intact, which results in a build-up of corneocytes and the appearance of dry, flaky skin.

◆ 원문 정보
저자: Harwood A, Nassereddin A, Krishnamurthy K
연도: 2019

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